INT221244

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pdpk1, Akt1) cytosol (Pdpk1, Akt1) signal transduction (Pdpk1, Akt1)
plasma membrane (Pdpk1, Akt1) kinase activity (Pdpk1, Akt1) transport (Akt1)
Pdpk1 (Mus musculus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 6 93.24 High High
adenocard 8 92.64 High High
Kinase C 76 42.24 Quite Low
potassium channel 152 21.32 Low Low
action potential duration 8 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
noradrenaline 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 232 64.88 Quite High
Apoptosis 32 18.64 Low Low
Cv Unclassified Under Development 136 5.00 Very Low Very Low Very Low
Reperfusion Injury 60 5.00 Very Low Very Low Very Low
Stress 38 5.00 Very Low Very Low Very Low
Targeted Disruption 16 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The resulting phosphatidylinositol 3,4-bisphosphate then activates phosphoinositide-dependent kinase 1 (PDK1) that in turn phosphorylates and activates Akt.
phosphoinositide-dependent kinase 1 Positive_regulation (phosphorylates) of Phosphorylation (phosphorylates) of Akt
1) Confidence 0.09 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.06 Pain Relevance 0.09
The resulting phosphatidylinositol 3,4-bisphosphate then activates phosphoinositide-dependent kinase 1 (PDK1) that in turn phosphorylates and activates Akt.
PDK1 Positive_regulation (phosphorylates) of Phosphorylation (phosphorylates) of Akt
2) Confidence 0.09 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.06 Pain Relevance 0.09

General Comments

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