INT221247

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Hspa9, Ptpn2) phosphatase activity (Ptpn2) unfolded protein binding (Hspa9)
mitochondrion (Hspa9) endoplasmic reticulum (Ptpn2) enzyme binding (Hspa9)
Anatomy Link Frequency
livers 1
Hspa9 (Mus musculus)
Ptpn2 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 42.08 Quite Low
Potency 1 7.24 Low Low
potassium channel 76 5.00 Very Low Very Low Very Low
Kinase C 38 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
action potential duration 4 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
noradrenaline 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 116 100.00 Very High Very High Very High
Targeted Disruption 8 96.80 Very High Very High Very High
Stress 19 66.36 Quite High
Tumor Necrosis Factor Receptor-associated Periodic Syndrome 1 49.24 Quite Low
Cv Unclassified Under Development 68 5.00 Very Low Very Low Very Low
Reperfusion Injury 30 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus in an elegant study, that has yet to be confirmed by others, mitochondria from mouse livers in which ANT1 and ANT2 had been knocked out were found to exhibit MPTP opening that was inhibited by CsA [62].
CsA Negative_regulation (inhibited) of MPTP in livers associated with parkinson's disease
1) Confidence 0.03 Published 2007 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2212780 Disease Relevance 0.67 Pain Relevance 0

General Comments

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