INT22128

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 1990
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 61
Total Number 63
Disease Relevance 70.52
Pain Relevance 6.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HIVEP1) intracellular (HIVEP1) DNA binding (HIVEP1)
cytoplasm (HIVEP1)
Anatomy Link Frequency
plasma 7
T cell 4
brain 3
blood 3
monocyte 2
HIVEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 116 99.98 Very High Very High Very High
Morphine 28 99.82 Very High Very High Very High
mu opioid receptor 11 99.68 Very High Very High Very High
agonist 14 99.54 Very High Very High Very High
chemokine 170 99.38 Very High Very High Very High
Glutamate 48 99.36 Very High Very High Very High
diabetic neuropathy 8 98.56 Very High Very High Very High
Central nervous system 233 98.04 Very High Very High Very High
Opioid 25 97.52 Very High Very High Very High
Inflammation 109 96.72 Very High Very High Very High
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 5070 100.00 Very High Very High Very High
Infection 1886 100.00 Very High Very High Very High
Leishmaniasis 16 100.00 Very High Very High Very High
Pain 125 99.98 Very High Very High Very High
Viral Meningitis 92 99.96 Very High Very High Very High
Cold Sores 1272 99.74 Very High Very High Very High
Hypertriglyceridemia 8 99.68 Very High Very High Very High
Neuroblastoma 2 99.60 Very High Very High Very High
Herpes Simplex Virus Infection 92 99.42 Very High Very High Very High
Opportunistic Infections 55 99.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An important finding of our study was that of the 564 women who claimed to have been tested for HIV some time during pregnancy, only 219 were confident in reporting test results.
Positive_regulation (tested) of HIV associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.43 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2365974 Disease Relevance 0.87 Pain Relevance 0
Reverse transcription (RT)–PCR detected v-GAAP messenger RNA (mRNA) from 2 h post infection (p.i.) onward and at 22 h p.i. in the presence of AraC.
Positive_regulation (detected) of v-GAAP associated with infection
2) Confidence 0.42 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1803007 Disease Relevance 0.42 Pain Relevance 0
These data indicate that h-GAAP is necessary for cell survival.


Positive_regulation (necessary) of h-GAAP
3) Confidence 0.39 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1803007 Disease Relevance 0.69 Pain Relevance 0.04
Morphine-induced transactivation of HIV-1 LTR in human neuroblastoma cells.
Positive_regulation (transactivation) of HIV-1 LTR associated with neuroblastoma, acquired immune deficiency syndrome or hiv infection and morphine
4) Confidence 0.36 Published 1990 Journal AIDS Res. Hum. Retroviruses Section Title Doc Link 2252636 Disease Relevance 1.23 Pain Relevance 0.45
Thus we cannot rule out the possibility that SAVVY increases the risk of HIV among certain users, such as women with above median coital frequency, numbers of partners, or gel use.
Positive_regulation (increases) of HIV associated with acquired immune deficiency syndrome or hiv infection
5) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2190795 Disease Relevance 0.52 Pain Relevance 0
HIV-1 gp120 up-regulation of the mu opioid receptor in TPA-differentiated HL-60 cells.
Positive_regulation (up-regulation) of HIV-1 in HL-60 associated with acquired immune deficiency syndrome or hiv infection and mu opioid receptor
6) Confidence 0.19 Published 2006 Journal Int. Immunopharmacol. Section Title Doc Link 16846840 Disease Relevance 0.69 Pain Relevance 0.63
First, it resulted in a significant increase in the number of people being tested for HIV34.
Positive_regulation (increase) of HIV34
7) Confidence 0.09 Published 2010 Journal International Journal of Epidemiology Section Body Doc Link PMC2992621 Disease Relevance 1.96 Pain Relevance 0
Beta-endorphin enhanced the synthesis of p-24 antigen and transactivation of HIV promoter.
Positive_regulation (transactivation) of HIV promoter associated with acquired immune deficiency syndrome or hiv infection
8) Confidence 0.08 Published 1995 Journal J. Neuroimmunol. Section Abstract Doc Link 7560019 Disease Relevance 0.70 Pain Relevance 0.23
It has been shown that CD4 localization in lipid rafts is required for p56lck activation and HIV-1 entry [15].
Positive_regulation (activation) of HIV-1 associated with acquired immune deficiency syndrome or hiv infection
9) Confidence 0.08 Published 2009 Journal Trials Section Body Doc Link PMC2705367 Disease Relevance 0.97 Pain Relevance 0
Mathematical modeling has predicted that post-integration inhibitors support the accumulation of cells carrying an integrated provirus, ultimately resulting in an accumulation of HIV-1-infected cells that counteracts the antiviral effect [13].
Positive_regulation (accumulation) of HIV-1 associated with acquired immune deficiency syndrome or hiv infection
10) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925957 Disease Relevance 0.66 Pain Relevance 0.08
Similar results were observed if the HIV-1 vector was incubated for only one hour with the A3-CCR5 cells before washing and mixing with PM-1 (data not shown).
Positive_regulation (incubated) of HIV-1 associated with acquired immune deficiency syndrome or hiv infection
11) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925957 Disease Relevance 0.74 Pain Relevance 0
In order to better interpret CSF findings, it is essential to understand what factors contribute to elevated CSF HIV RNA concentrations.
Positive_regulation (elevated) of HIV in CSF associated with acquired immune deficiency syndrome or hiv infection
12) Confidence 0.05 Published 2005 Journal BMC Infect Dis Section Body Doc Link PMC1299327 Disease Relevance 1.49 Pain Relevance 0.05
Firstly the combination of HIV and VL is increasing and it is very difficult to diagnose and treat.
Positive_regulation (increasing) of HIV associated with leishmaniasis and acquired immune deficiency syndrome or hiv infection
13) Confidence 0.05 Published 2008 Journal Cases J Section Body Doc Link PMC2561008 Disease Relevance 1.82 Pain Relevance 0.09
B translocates to the nucleus and induces the activation of the HIV-1 LTR (Fig. 3 and 4).
Positive_regulation (activation) of HIV in nucleus associated with acquired immune deficiency syndrome or hiv infection
14) Confidence 0.05 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.94 Pain Relevance 0.27
Collectively, these data demonstrate that vaccination with MVA-CMDR induces a potent insert-directed proliferative response that is route-dependent and cross-reactive between CRF01_AE and subtype B HIV-1 isolates.


Positive_regulation (induces) of HIV associated with acquired immune deficiency syndrome or hiv infection
15) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981570 Disease Relevance 0.26 Pain Relevance 0.04
OBJECTIVE: In this study, we sought to determine the possible mechanisms by which morphine upregulates HIV infection of human blood monocyte-derived macrophages (MDM).
Spec (possible) Positive_regulation (upregulates) of HIV in blood
16) Confidence 0.04 Published 2002 Journal J. Investig. Med. Section Body Doc Link 12425430 Disease Relevance 0.37 Pain Relevance 0
When HIV symptoms were induced by a "genie" or by "mapepo", prayers could be used as an effective tool to eliminate the disease.
Positive_regulation (induced) of HIV associated with acquired immune deficiency syndrome or hiv infection and disease
17) Confidence 0.04 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2916904 Disease Relevance 0.57 Pain Relevance 0
This is important because cyclin T1 is one-half of the positive transcriptional elongation factor b (P-TEFb) complex necessary for the binding of Tat to TAR for the induction of HIV-1 transcription.
Positive_regulation (induction) of HIV associated with acquired immune deficiency syndrome or hiv infection
18) Confidence 0.04 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.71 Pain Relevance 0
B site(s) located immediately upstream of the Sp sites in the enhancer in HIV and SIV result in Sp-NF-?
Positive_regulation (result) of HIV associated with acquired immune deficiency syndrome or hiv infection
19) Confidence 0.04 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.24 Pain Relevance 0
As cells of the monocyte lineage differentiate, the ratio of Sp1 to Sp3 increases, resulting in increased HIV-1 transcription (McAllister and Wigdahl, unpublished observations).
Positive_regulation (increased) of HIV in monocyte associated with acquired immune deficiency syndrome or hiv infection
20) Confidence 0.04 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.48 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox