INT221350

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 2
RT1-CE1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Osteoarthritis 56 87.04 High High
tolerance 2 76.24 Quite High
Inflammatory mediators 1 74.52 Quite High
fibrosis 23 69.04 Quite High
cytokine 17 52.08 Quite High
agonist 10 50.00 Quite Low
Inflammation 4 39.48 Quite Low
Inflammatory response 12 12.88 Low Low
Pain 10 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 55 87.04 High High
Weight Gain 4 75.12 Quite High
Injury 4 74.88 Quite High
INFLAMMATION 17 74.12 Quite High
Fibrosis 15 69.04 Quite High
Asthma 6 66.72 Quite High
Hypertrophy 12 50.00 Quite Low
Disease 4 50.00 Quite Low
Pulmonary Disease 10 42.20 Quite Low
Graft Vs Host Disease 1 28.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clenbuterol administration exhibited an apparent 16% increase in total MHC protein expression relative to total protein (data not presented), although there was no change in the composition of the different MHC isoforms (Table I).


Positive_regulation (increase) of Gene_expression (expression) of MHC protein
1) Confidence 0.17 Published 2010 Journal Osteoarthritis and Cartilage Section Body Doc Link PMC2849930 Disease Relevance 0.27 Pain Relevance 0.07
TNF-alpha increases class I MHC expression and has been associated with acute and chronic rejection in recipients of lung and other allografts [21,36-38].
Positive_regulation (increases) of Gene_expression (expression) of class I MHC in lung
2) Confidence 0.08 Published 2007 Journal Respir Res Section Body Doc Link PMC2213655 Disease Relevance 0.39 Pain Relevance 0.16

General Comments

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