INT221383

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, Ptger2) plasma membrane (Tlr4, Ptger2) intracellular (Tlr4)
signal transducer activity (Ptger2) cytoplasm (Tlr4)
Anatomy Link Frequency
lung 2
Tlr4 (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 14 96.72 Very High Very High Very High
Inflammation 44 77.80 Quite High
Inflammatory response 14 68.68 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pyramidal cell 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 214 99.48 Very High Very High Very High
INFLAMMATION 72 96.32 Very High Very High Very High
Nicotine Addiction 40 94.92 High High
Pneumonia 2 35.24 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Lower Respiratory Tract Infection 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Pseudomonas Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No correlation was observed between basal and LPS-induced release of PGE2 and LTB4 by BES and clinical and functional parameters of COPD and non-COPD patients (data not shown).


LPS Positive_regulation (induced) of Localization (release) of PGE2 associated with pulmonary disease
1) Confidence 0.00 Published 2007 Journal Respir Res Section Body Doc Link PMC2214730 Disease Relevance 0.82 Pain Relevance 0.04
Interestingly, LPS induced a higher release of IL-8, but not PGE2 and LTB4 in COPD BES (p < 0.001) which correlated with lung function changes.


LPS Neg (not) Positive_regulation (induced) of Localization (release) of PGE2 in lung associated with pulmonary disease
2) Confidence 0.00 Published 2007 Journal Respir Res Section Abstract Doc Link PMC2214730 Disease Relevance 0.97 Pain Relevance 0.20

General Comments

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