INT221385

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.79
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, IL8) intracellular (Tlr4, IL8) extracellular space (IL8)
extracellular region (IL8) plasma membrane (Tlr4) cytoplasm (Tlr4)
Anatomy Link Frequency
epithelial cell 1
Tlr4 (Mus musculus)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 22 95.08 Very High Very High Very High
Inflammatory mediators 7 88.96 High High
Inflammatory response 7 72.96 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 107 99.16 Very High Very High Very High
Nicotine Addiction 20 98.08 Very High Very High Very High
INFLAMMATION 36 95.08 Very High Very High Very High
Infection 1 41.32 Quite Low
Disease 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Lower Respiratory Tract Infection 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Pseudomonas Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As expected, it should be pointed that LPS-induced IL-8 levels varied among COPD patients, suggesting that epithelial cell responsiveness to LPS cannot alone explain the complex inflammatory process of COPD.
LPS Positive_regulation (induced) of IL-8 in epithelial cell associated with pulmonary disease and inflammation
1) Confidence 0.05 Published 2007 Journal Respir Res Section Body Doc Link PMC2214730 Disease Relevance 1.79 Pain Relevance 0.20

General Comments

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