INT221416

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B, NFKB2) signal transduction (IL1B, NFKB2) nucleoplasm (NFKB2)
aging (IL1B) extracellular matrix organization (NFKB2) DNA binding (NFKB2)
IL1B (Homo sapiens)
NFKB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 16 99.82 Very High Very High Very High
Inflammation 20 95.88 Very High Very High Very High
Inflammatory stimuli 1 63.84 Quite High
Inflammatory response 4 42.96 Quite Low
tolerance 13 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 95.88 Very High Very High Very High
Mycobacterial Infection 19 94.36 High High
Disease 7 77.12 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 32 75.48 Quite High
Infection 7 69.52 Quite High
Graft Vs Host Disease 1 67.92 Quite High
Inflammatory Bowel Disease 2 66.24 Quite High
Immune Reconstitution Inflammatory Syndrome 31 50.00 Quite Low
Sepsis 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cytokines such as IL-1 can also stimulate the NFkB binding molecule to activate NFkB [54-56], which induces the expression of cyclooxygenase-2 (COX-2), which consequently leads to tissue inflammation at the site where latent TB antigens are located.
IL-1 Binding (binding) of Positive_regulation (activate) of NFkB associated with mycobacterial infection, inflammation and cytokine
1) Confidence 0.02 Published 2007 Journal AIDS Res Ther Section Body Doc Link PMC2216023 Disease Relevance 0.88 Pain Relevance 0.23

General Comments

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