INT221432

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.59
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB2) extracellular matrix organization (NFKB2) DNA binding (NFKB2)
cytoplasm (NFKB2) cytosol (NFKB2) signal transduction (NFKB2)
NFKB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 33 99.96 Very High Very High Very High
cytokine 29 99.54 Very High Very High Very High
methotrexate 2 85.52 High High
Inflammatory stimuli 1 61.76 Quite High
Inflammatory response 4 42.40 Quite Low
Pain 2 20.20 Low Low
tolerance 13 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 35 99.96 Very High Very High Very High
Mucositis 55 99.40 Very High Very High Very High
Mycobacterial Infection 19 93.32 High High
Apoptosis 7 85.88 High High
Stress 1 85.00 Quite High
Disease 10 76.56 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 32 74.92 Quite High
Infection 11 68.96 Quite High
Graft Vs Host Disease 1 67.36 Quite High
Injury 23 67.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cytokines such as IL-1 can also stimulate the NFkB binding molecule to activate NFkB [54-56], which induces the expression of cyclooxygenase-2 (COX-2), which consequently leads to tissue inflammation at the site where latent TB antigens are located.
Positive_regulation (stimulate) of NFkB Binding (binding) of associated with mycobacterial infection, inflammation and cytokine
1) Confidence 0.12 Published 2007 Journal AIDS Res Ther Section Body Doc Link PMC2216023 Disease Relevance 0.87 Pain Relevance 0.23
mediators, TNF and NFkB, have been shown to increase along the length of the
Positive_regulation (increase) of NFkB Binding (mediators) of
2) Confidence 0.07 Published 2008 Journal Journal of Oncology Section Body Doc Link PMC2648637 Disease Relevance 0.73 Pain Relevance 0.31

General Comments

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