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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (TNFSF11) extracellular space (TNFSF11) extracellular region (TNFSF11)
plasma membrane (TNFSF11) intracellular (TNFSF11) response to stress (TNFSF11)
Anatomy Link Frequency
osteoclast 2
TNFSF11 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 3 10.64 Low Low
agonist 5 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 21 98.36 Very High Very High Very High
Immunotherapy Of Cancer 8 81.48 Quite High
Osteoporotic Fractures 4 78.64 Quite High
Reprotox - General 2 5 77.64 Quite High
Lymphatic System Cancer 1 76.12 Quite High
Cancer 11 75.44 Quite High
Postmenopausal Osteoporosis 4 63.60 Quite High
Malignant Neoplastic Disease 2 40.16 Quite Low
Breast Cancer 14 32.56 Quite Low
Hypercalcemia 18 32.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, it enhances the osteoblastic production of osteoprotegerin, which has anti-osteoclastic properties because of its ability to bind to rankl and subsequently to block the rankl/rank interaction required for osteoclast recruitment and activation 59,60.
Positive_regulation (required) of rankl Binding (interaction) of in osteoclast associated with osteoporosis
1) Confidence 0.15 Published 2008 Journal Current Oncology Section Body Doc Link PMC2216420 Disease Relevance 0.98 Pain Relevance 0

General Comments

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