INT221545

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.40
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema3a) extracellular region (Sema3a)
Sema3a (Mus musculus)
Pain Link Frequency Relevance Heat
Antinociceptive 2 98.72 Very High Very High Very High
Pain 2 86.80 High High
qutenza 6 80.96 Quite High
vanilloid receptor subtype 1 2 69.68 Quite High
Inflammation 14 66.24 Quite High
Nerve growth factor 98 60.56 Quite High
dorsal root ganglion 37 31.60 Quite Low
substance P 16 5.00 Very Low Very Low Very Low
c fibre 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 8 98.34 Very High Very High Very High
Eczema 216 97.54 Very High Very High Very High
Shock 24 96.44 Very High Very High Very High
Acanthosis 4 95.72 Very High Very High Very High
Pruritus 48 76.44 Quite High
INFLAMMATION 10 66.24 Quite High
Ganglion Cysts 38 50.00 Quite Low
Recurrence 2 26.16 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Hypersensitivity 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, Sema3A and NRP-1 of its receptors expressed in human keratinocytes52 may be relevant to the above-mentioned suppressive effect of Sema3A on acanthosis observed in our present experiment.
Sema3A Binding (receptors) of associated with acanthosis
1) Confidence 0.33 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 0.49 Pain Relevance 0.06
In our experiments regarding the effects of Sema3A on AD-like lesions, no apparent abnormalities in antinociceptive response as well as in general symptoms were observed on local treatment with Sema3A.
Sema3A Binding (treatment) of associated with congenital anomalies, eczema and antinociceptive
2) Confidence 0.29 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946701 Disease Relevance 0.73 Pain Relevance 0.47
A complex of PlexinA1 and neuropilin 1 (NP1) was shown to act as a receptor for Sema3A [10,11].
Sema3A Binding (receptor) of
3) Confidence 0.24 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0.19 Pain Relevance 0

General Comments

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