INT221549

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Context Info
Confidence 0.70
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.66
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Fes) Golgi apparatus (Fes) plasma membrane (Fes)
cytoskeleton (Fes) kinase activity (Fes) cytoplasm (Fes)
Anatomy Link Frequency
embryos 1
Fes (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 111 96.76 Very High Very High Very High
withdrawal 3 70.20 Quite High
Root ganglion neuron 3 5.00 Very Low Very Low Very Low
nociceptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 114 96.76 Very High Very High Very High
Apoptosis 9 82.68 Quite High
Death 3 76.52 Quite High
Wallerian Degeneration 3 59.64 Quite High
Shock 66 54.68 Quite High
Adhesions 3 6.56 Low Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fps has been shown to associate with microtubules by Takahashi and colleagues, who also observed Fps co-localizing with sites of microtubule nucleation and bundling in transfected Cos-7 cells; furthermore, the observed Fps co-localization with ?
Localization (localization) of Fps
1) Confidence 0.70 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0.05 Pain Relevance 0
Fps and Fer were immunoprecipitated from wt mouse brains of E18 embryos, neonates and adults.
Localization (immunoprecipitated) of Fps in embryos
2) Confidence 0.70 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0 Pain Relevance 0
However, the addition of Sema3A to the media promoted additional axon retraction of wt but not the fps-/- axons.
Localization (retraction) of fps
3) Confidence 0.61 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0.61 Pain Relevance 0.19

General Comments

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