INT221652

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.35 Pain Relevance 0.09

extracellular region (Ngf, Ngrn) cell differentiation (Ngrn) signal transduction (Ngf) extracellular space (Ngf) nucleus (Ngrn) molecular_function (Ngrn)

Anatomy Link Frequency embryos 2 Ngf (Mus musculus) Ngrn (Mus musculus)

Pain Link Frequency Relevance Heat dorsal root ganglion 74 95.48 withdrawal 2 5.00 Root ganglion neuron 2 5.00 nociceptor 2 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 76 95.48 Shock 44 90.76 Targeted Disruption 6 12.48 Sprains And Strains 4 7.28 Apoptosis 6 5.00 Death 2 5.00 Adhesions 2 5.00 Wallerian Degeneration 2 5.00 Urological Neuroanatomy 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

DRGs from wild type and ferDR/DR embryos were again grown overnight in the presence of NGF to promote axon outgrowth.

NGF Positive_regulation (promote) of outgrowth in embryos

1) Confidence 0.01 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0.07 Pain Relevance 0

DRGs from wt and ferDR/DR E14 embryos were cultured overnight on collagen-matrigel in the presence of NGF to induce axon outgrowth.

NGF Positive_regulation (induce) of outgrowth in embryos

2) Confidence 0.01 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC2217550 Disease Relevance 0.28 Pain Relevance 0.09

General Comments

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