INT221674

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.28
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Erbb2) plasma membrane (Erbb2) nucleus (Erbb2)
kinase activity (Erbb2) cytoplasm (Erbb2)
Erbb2 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 1 73.76 Quite High
imagery 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 25 100.00 Very High Very High Very High
Advanced Or Metastatic Breast Cancer 41 99.36 Very High Very High Very High
Recurrence 6 82.64 Quite High
Cancer 32 76.16 Quite High
Hemorrhage 5 75.68 Quite High
Pressure And Volume Under Development 17 71.40 Quite High
Nose Bleeds 1 69.76 Quite High
Proteinuria 10 69.16 Quite High
Toxicity 8 66.36 Quite High
Breast Cancer 39 59.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with HER-2 positive disease were permitted to be enrolled if they had had prior trastuzumab therapy.
Localization (disease) of HER-2 associated with disease
1) Confidence 0.38 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727886 Disease Relevance 0.94 Pain Relevance 0
In other published studies using non-anthracycline based chemoendocrine agents [11], it was reported that positive ER, absence of c-erbB2 and decrease in Ki-67 were associated with a good clinical response.
Neg (absence) Localization (absence) of c-erbB2
2) Confidence 0.12 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2217558 Disease Relevance 0.34 Pain Relevance 0.07

General Comments

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