INT221678

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.78
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Mki67) nucleolus (Mki67) nucleus (Mki67)
intracellular (Mki67) cytoplasm (Mki67)
Mki67 (Mus musculus)
Pain Link Frequency Relevance Heat
fortral 3 61.80 Quite High
methotrexate 1 57.80 Quite High
Inflammation 2 21.88 Low Low
Taxol 14 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 27 99.02 Very High Very High Very High
Cancer 144 98.98 Very High Very High Very High
Apoptosis 43 98.48 Very High Very High Very High
Triple Negative Breast Cancer 15 86.32 High High
Recurrence 6 62.64 Quite High
Adenocarcinoma 10 50.12 Quite High
Breast Cancer 16 50.00 Quite Low
Disease 7 48.84 Quite Low
Inflammatory Breast Neoplasms 2 22.48 Low Low
Body Weight 2 16.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the parameters investigated, low histologic grade, positive ER, positive PR, positive bcl-2 and low level of Ki-67 were associated with prolonged RFS in univariate analysis.
Protein_catabolism (grade) of Ki-67
1) Confidence 0.33 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2217558 Disease Relevance 0.15 Pain Relevance 0.03
To determine the effect of the therapies on tumor cell apoptosis and proliferation, tumor sections were stained with antibodies recognizing cleaved caspase-3 and Ki67, respectively.
Protein_catabolism (cleaved) of Ki67 associated with cancer and apoptosis
2) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2781164 Disease Relevance 0.85 Pain Relevance 0
Next, in order to further characterize this effect, we evaluated the growth phase of these pancreatic cancer cells under these conditions by co-staining for cleaved caspase-3 and the proliferation maker Ki-67.
Protein_catabolism (cleaved) of Ki-67 associated with pancreatic cancer
3) Confidence 0.11 Published 2009 Journal J Transl Med Section Body Doc Link PMC2669042 Disease Relevance 0.78 Pain Relevance 0.06

General Comments

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