INT221746

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.92
Pain Relevance 2.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) signal transduction (Ngf) extracellular space (Ngf)
aging (Ngf) extracellular region (Ngf) plasma membrane (Ntrk1)
Anatomy Link Frequency
plasma 2
Ngf (Rattus norvegicus)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 6 100.00 Very High Very High Very High
opioid receptor 246 97.72 Very High Very High Very High
substance P 10 96.84 Very High Very High Very High
agonist 60 93.88 High High
intrathecal 2 92.80 High High
analgesia 18 91.88 High High
dorsal root ganglion 24 90.56 High High
Neuropeptide 4 73.16 Quite High
qutenza 6 65.72 Quite High
Kinase C 6 61.56 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 26 90.56 High High
Targeted Disruption 4 87.56 High High
Pain 44 50.00 Quite Low
INFLAMMATION 20 36.88 Quite Low
Depression 2 5.44 Low Low
Urological Neuroanatomy 20 5.00 Very Low Very Low Very Low
Neuropathic Pain 12 5.00 Very Low Very Low Very Low
Nociception 10 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of the TrkA signaling pathway by nerve growth factor (NGF) regulates the later (post-ER) events in the anterograde trafficking of intracellular DOR, which is required to maintain the intracellular pool of DOR available for plasma membrane insertion [18].
NGF Positive_regulation (Activation) of TrkA in plasma associated with nerve growth factor and opioid receptor
1) Confidence 0.02 Published 2007 Journal Mol Pain Section Body Doc Link PMC2219988 Disease Relevance 0.46 Pain Relevance 1.44
Activation of the TrkA signaling pathway by nerve growth factor (NGF) regulates the later (post-ER) events in the anterograde trafficking of intracellular DOR, which is required to maintain the intracellular pool of DOR available for plasma membrane insertion [18].
nerve growth factor Positive_regulation (Activation) of TrkA in plasma associated with nerve growth factor and opioid receptor
2) Confidence 0.02 Published 2007 Journal Mol Pain Section Body Doc Link PMC2219988 Disease Relevance 0.46 Pain Relevance 1.44

General Comments

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