INT221783

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.39
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nlrp1a, Camk4) signal transduction (Camk4) nucleocytoplasmic transport (Camk4)
cell death (Nlrp1a) enzyme binding (Nlrp1a) kinase activity (Camk4)
Nlrp1a (Mus musculus)
Camk4 (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 94 100.00 Very High Very High Very High
amygdala 6 97.20 Very High Very High Very High
Hippocampus 6 89.84 High High
Central nervous system 2 86.12 High High
long-term potentiation 2 55.80 Quite High
Action potential 6 25.12 Quite Low
Eae 16 25.08 Quite Low
anesthesia 4 5.00 Very Low Very Low Very Low
narcan 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 68 99.20 Very High Very High Very High
Stress 2 86.80 High High
Cytomegalovirus Infection 4 81.84 Quite High
Targeted Disruption 14 74.64 Quite High
Cognitive Disorder 2 72.56 Quite High
Congenital Anomalies 6 54.24 Quite High
Sprains And Strains 2 52.68 Quite High
Post-traumatic Stress Disorder 20 9.08 Low Low
Depression 4 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we detected an anxiogenic phenotype after NAc-specific suppression of CaMKIV function.
NAc Negative_regulation (suppression) of CaMKIV associated with nucleus accumbens
1) Confidence 0.08 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC2219998 Disease Relevance 0.72 Pain Relevance 0.38
The results obtained indicate that NAc-specific suppression of CaMKIV activity increased anxiety-related behaviour whereas sensorimotor gating was unaffected.


NAc Negative_regulation (suppression) of CaMKIV associated with nucleus accumbens and anxiety disorder
2) Confidence 0.08 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC2219998 Disease Relevance 0.67 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox