INT221791

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.98
Pain Relevance 1.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TH1L) nucleus (TH1L)
TH1L (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 228 100.00 Very High Very High Very High
Inflammation 175 99.14 Very High Very High Very High
antagonist 34 96.80 Very High Very High Very High
rheumatoid arthritis 149 92.08 High High
Osteoarthritis 10 91.92 High High
Arthritis 36 84.00 Quite High
aspirin 1 64.96 Quite High
withdrawal 2 63.24 Quite High
methotrexate 20 55.40 Quite High
corticosteroid 12 55.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 180 99.14 Very High Very High Very High
Carcinoma 18 95.36 Very High Very High Very High
Asthma 315 92.56 High High
Rheumatoid Arthritis 149 92.08 High High
Osteoarthritis 10 91.92 High High
Autoimmune Disease 21 91.60 High High
Disease 64 85.84 High High
Papillomavirus Infection 58 85.28 High High
Arthritis 42 84.00 Quite High
Diabetes Mellitus 4 83.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have also studied cytokines associated with the function of Th2 (IL-4 and IL-10) and Th1 (IL-2, IL-12 (p70), and INF?)
Transcription (function) of Th1 associated with cytokine
1) Confidence 0.45 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991033 Disease Relevance 1.18 Pain Relevance 0.75
Rheumatoid inflammation is characterized by a dominant pathogenic Th1 drive
Transcription (drive) of Th1 associated with inflammation
2) Confidence 0.32 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833981 Disease Relevance 1.42 Pain Relevance 0.42
Furthermore, aminophylline decreases Th2-related cytokine mRNA expression but increases Th1-related cytokines mRNA expression [35].


Transcription (expression) of Th1-related associated with cytokine
3) Confidence 0.25 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.62 Pain Relevance 0.40
In order to characterize a possible Th-1 type
Transcription (characterize) of Th-1
4) Confidence 0.20 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC2220028 Disease Relevance 0.76 Pain Relevance 0.26

General Comments

This test has worked.

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