INT221796

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.19
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tfap2a) Golgi apparatus (Tfap2a) nucleus (Tfap2a)
DNA binding (Tfap2a) transcription factor binding (Tfap2a) cytoplasm (Tfap2a)
Anatomy Link Frequency
adipocyte 2
Tfap2a (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 18 99.08 Very High Very High Very High
Potency 2 98.78 Very High Very High Very High
Inflammation 67 96.72 Very High Very High Very High
antagonist 4 93.52 High High
qutenza 5 85.80 High High
Cannabinoid 46 65.76 Quite High
Endocannabinoid 9 56.64 Quite High
Inflammatory response 12 51.36 Quite High
Inflammatory mediators 5 16.68 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 85 96.72 Very High Very High Very High
Obesity 93 93.52 High High
Insulin Resistance 9 88.48 High High
Hypercholesterolemia 2 80.40 Quite High
Diabetes Mellitus 7 78.08 Quite High
Targeted Disruption 5 70.84 Quite High
Vomiting 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Poisoning 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
transcriptional potency in 3T3L1 cells, forced 3T3L1 adipocyte differentiation, and induced the expression of adipocyte differentiation marker aP2.
Positive_regulation (induced) of Gene_expression (expression) of aP2 in adipocyte associated with potency
1) Confidence 0.10 Published 2007 Journal PPAR Research Section Body Doc Link PMC2220031 Disease Relevance 0.14 Pain Relevance 0.29
, it not only enhances the expressions of adiponectin and aP2 but also inhibits the TNF-?
Positive_regulation (enhances) of Gene_expression (expressions) of aP2
2) Confidence 0.06 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2876247 Disease Relevance 1.05 Pain Relevance 0.54

General Comments

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