INT221874

Context Info Confidence 0.00 First Reported 2007 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 3 Total Number 4 Disease Relevance 1.29 Pain Relevance 0.71

Ctrcts (Mus musculus)

Pain Link Frequency Relevance Heat Pain 22 99.22 addiction 6 95.36 ischemia 2 91.92 Inflammation 4 67.64 depression 48 45.20 tolerance 30 5.00 cva 15 5.00 beta blocker 6 5.00 Restless leg syndrome 3 5.00 drug abuse 3 5.00

Disease Link Frequency Relevance Heat Pain 19 99.22 Cv Unclassified Under Development 5 91.92 Infection 4 77.68 Amputation 7 77.32 Osteomyelitis 3 75.84 INFLAMMATION 4 67.64 Systemic Sclerosis 38 66.08 Ulcers 18 56.44 Stroke 318 52.88 Depression 51 45.20

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Pain is a pivotal symptom because it seems associated with severity of DU.

severity Binding (associated) of associated with pain

1) Confidence 0.00 Published 2010 Journal International Journal of Rheumatology Section Body Doc Link PMC2938432 Disease Relevance 1.23 Pain Relevance 0.63

The model will include baseline impairment severity, categorical assessment time and their interactions.

severity Binding (interactions) of

2) Confidence 0.00 Published 2007 Journal BMC Neurol Section Body Doc Link PMC2222229 Disease Relevance 0.05 Pain Relevance 0.05

To test whether initial locomotor severity interacts with the number of treatment sessions to affect the gait speed immediately following the 12th, 24th, and 36th sessions.

severity Spec (whether) Binding (interacts) of

3) Confidence 0.00 Published 2007 Journal BMC Neurol Section Body Doc Link PMC2222229 Disease Relevance 0 Pain Relevance 0

The number of locomotor training sessions will interact with baseline locomotor impairment severity such that (1) individuals with more severe initial walking impairment will demonstrate greater improvements in gait speed from an increasing number of training sessions and (2) individuals with less severe initial walking impairment will not benefit from more extended training.

severity Binding (interact) of

4) Confidence 0.00 Published 2007 Journal BMC Neurol Section Body Doc Link PMC2222229 Disease Relevance 0 Pain Relevance 0.03

General Comments

This test has worked.