INT221918

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (TRPV4, TRPM8) cell death (TRPV4) plasma membrane (TRPV4)
TRPV4 (Homo sapiens)
TRPM8 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 20 98.60 Very High Very High Very High
qutenza 2 97.68 Very High Very High Very High
TRP channel 5 94.40 High High
antagonist 27 81.20 Quite High
Potency 3 42.16 Quite Low
Pain 16 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Analgesic 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Cold hyperalgesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 16 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 3 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PDD activated TRPV4, and icilin activated TRPM8 in cell based assays that measure agonist-induced increases in intracellular calcium in CHO cells recombinantly expressing the appropriate TRP channel.
TRPV4 Positive_regulation (activated) of TRPM8 associated with trp channel and agonist
1) Confidence 0.05 Published 2007 Journal Mol Pain Section Body Doc Link PMC2222611 Disease Relevance 0 Pain Relevance 0.28

General Comments

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