INT221958

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (CDK5R1, CDK5) cytoplasm (CDK5R1, CDK5) cytosol (CDK5R1, CDK5)
cell proliferation (CDK5R1, CDK5) nucleus (CDK5R1, CDK5) plasma membrane (CDK5R1, CDK5)
Anatomy Link Frequency
central nervous system 2
CDK5R1 (Homo sapiens)
CDK5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 11 98.48 Very High Very High Very High
Neuritis 1 11.92 Low Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Malformation 9 98.16 Very High Very High Very High
Cognitive Disorder 4 96.60 Very High Very High Very High
Neurodegenerative Disease 11 95.64 Very High Very High Very High
Convulsion 1 32.72 Quite Low
Neuritis 1 11.92 Low Low
Neuroblastoma 9 5.00 Very Low Very Low Very Low
Intellectual Impairment 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CDK5R1 (Cyclin-dependent kinase 5 regulatory subunit 1) encodes for p35, a protein required for the activation of cyclin-dependent kinase 5 (CDK5), whose activity plays a key role in central nervous system development [1].
p35 Positive_regulation (required) of Positive_regulation (activation) of CDK5 in central nervous system associated with nervous system malformation and central nervous system
1) Confidence 0.36 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC2222623 Disease Relevance 0.38 Pain Relevance 0.10

General Comments

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