INT221959

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (CDK5, CDK5R1) cytoplasm (CDK5, CDK5R1) cell proliferation (CDK5, CDK5R1)
cytosol (CDK5, CDK5R1) nucleus (CDK5, CDK5R1) plasma membrane (CDK5, CDK5R1)
CDK5 (Homo sapiens)
CDK5R1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 11 96.68 Very High Very High Very High
cerebral cortex 1 59.60 Quite High
Neuritis 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Malformation 9 97.16 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 2 97.12 Very High Very High Very High
Neurodegenerative Disease 11 95.16 Very High Very High Very High
Congenital Anomalies 1 62.96 Quite High
Intellectual Impairment 5 51.68 Quite High
Syndrome 3 46.56 Quite Low
Cognitive Disorder 4 25.44 Quite Low
Disease 4 23.28 Low Low
Neuroblastoma 9 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The active CDK5-p35 complex is strongly involved in neurofilament phosphorylation and its aberrant hyperactivity has been shown to be implicated in neurodegenerative diseases [58].
CDK5 Binding (complex) of p35 associated with neurodegenerative disease and attention deficit hyperactivity disorder
1) Confidence 0.28 Published 2007 Journal BMC Mol Biol Section Body Doc Link PMC2222623 Disease Relevance 0.53 Pain Relevance 0.10

General Comments

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