INT221984

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 5.20
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp)
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 38 97.44 Very High Very High Very High
Inflammatory marker 3 95.80 Very High Very High Very High
Angina 7 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
beta blocker 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain refractory 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 16 100.00 Very High Very High Very High
Infection 10 99.64 Very High Very High Very High
Coronary Artery Disease 143 99.58 Very High Very High Very High
Pneumonia 51 99.44 Very High Very High Very High
INFLAMMATION 40 97.44 Very High Very High Very High
Hyperplasia 17 95.48 Very High Very High Very High
Diabetes Mellitus 93 91.08 High High
Disease 6 88.60 High High
Calcification 93 86.04 High High
Acute Coronary Syndrome 6 82.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Statin treatment in especially IHD patients could also influence the levels of both YKL-40 and hsCRP, but without this treatment we would expect even higher levels of both markers in the IHD groups.
Regulation (influence) of CRP Binding (levels) of associated with coronary artery disease
1) Confidence 0.44 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3016330 Disease Relevance 2.31 Pain Relevance 0.21
A recent meta-analysis has shown that associations of CRP with ischemic vascular disease depend considerably on conventional risk factors and other markers of inflammation making a causal role of CRP in the development of CAD also unlikely [17].
Regulation (depend) of CRP Binding (associations) of associated with coronary artery disease, inflammation and increased venous pressure under development
2) Confidence 0.10 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2994837 Disease Relevance 0.93 Pain Relevance 0.09
Nonetheless, no difference between the two groups were observed indicating that Cpn infection does not have an effect on the presence of CRP in the vascular wall at the time point examined.
Regulation (effect) of CRP Spec (examined) Binding (presence) of associated with pneumonia and infection
3) Confidence 0.04 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.18 Pain Relevance 0.06
Epidemiologic studies have shown a fairly consistent independent association between high-sensitivity CRP (hs-CRP) elevations and coronary risk, although a causal relation has not yet been established.41,42
Neg (independent) Regulation (independent) of hs-CRP Binding (association) of
4) Confidence 0.04 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2672446 Disease Relevance 0.77 Pain Relevance 0.13

General Comments

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