INT221999

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Context Info
Confidence 0.65
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.10
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (F7) extracellular space (F7) extracellular region (F7)
plasma membrane (F7)
Anatomy Link Frequency
plasma 1
F7 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 5 75.60 Quite High
Spinal cord 2 71.20 Quite High
ischemia 3 70.24 Quite High
Cauda equina syndrome 6 66.36 Quite High
peripheral neuropathy 1 50.68 Quite High
iatrogenic 1 50.00 Quite Low
Action potential 2 19.44 Low Low
Pain 7 14.72 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
epidural 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombophilia 4 98.20 Very High Very High Very High
Obesity 2 96.54 Very High Very High Very High
Myocardial Infarction 2 93.84 High High
Embolism 3 88.24 High High
Syndrome 4 87.60 High High
Coagulation Disorder 3 86.00 High High
Thrombosis 9 82.48 Quite High
Disease 6 79.64 Quite High
Increased Venous Pressure Under Development 3 77.36 Quite High
Aneurism 2 74.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, obese people, like our patient, have higher plasminogen activator inhibitor type 1 plasma levels than normal controls, resulting in a hypofibrinolytic state, and elevated plasma levels of coagulation factor VII, fibrinogen and tissue factor, leading to a hypercoagulability state [7–9].
Gene_expression (levels) of coagulation factor VII in plasma associated with thrombophilia and obesity
1) Confidence 0.65 Published 2007 Journal J Neurol Section Body Doc Link PMC2780628 Disease Relevance 1.54 Pain Relevance 0.20
Furthermore, following abrupt discontinuation of heparin treatment, there can arise a transient increase in thrombin activity associated with a increase in activated protein C function.[11]

- Warfarin affects the synthesis of both procoagulant (factors II, VII, IX and X) and anticoagulant proteins (protein C and its co-factor protein S).[12] In the initial stages after commencement of warfarin, production of both factor VII along with that of proteins C and S are reduced.

Gene_expression (production) of factor VII
2) Confidence 0.19 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC2222673 Disease Relevance 0.56 Pain Relevance 0

General Comments

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