INT222012

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Map2k3)
Anatomy Link Frequency
lung 2
Map2k3 (Mus musculus)
Pain Link Frequency Relevance Heat
Mechanotransduction 4 88.24 High High
Inflammation 36 87.84 High High
metalloproteinase 6 72.08 Quite High
cytokine 8 71.48 Quite High
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 8 99.74 Very High Very High Very High
Lung Injury 116 98.18 Very High Very High Very High
Injury 16 89.00 High High
INFLAMMATION 36 87.84 High High
Disease 2 84.36 Quite High
Necrosis 6 72.08 Quite High
Cancer 4 71.72 Quite High
Apoptosis 32 55.52 Quite High
Pneumonia 2 32.08 Quite Low
Death 14 25.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice deficient in MKK3 and JNK1 are less susceptible to ventilator-induced lung injury
Negative_regulation (deficient) of MKK3 in lung associated with lung injury
1) Confidence 0.41 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2223071 Disease Relevance 0.73 Pain Relevance 0.12
We measured lung injury parameters in response to ventilation in C57/BL6 (wild-type) mice and strains genetically deficient in MKK3 and JNK1.
Negative_regulation (deficient) of MKK3 in lung associated with lung injury and sprains and strains
2) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2223071 Disease Relevance 0.89 Pain Relevance 0.16

General Comments

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