INT222042

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.72
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGB1) plasma membrane (ITGB1)
Anatomy Link Frequency
fibroblast 1
stem cells 1
ITGB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 118 72.48 Quite High
imagery 4 52.56 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Peripheral Arterial Disease 51 97.96 Very High Very High Very High
Hypersensitivity 2 94.08 High High
Cancer 28 58.16 Quite High
Obesity 3 20.40 Low Low
Malignant Neoplastic Disease 6 18.16 Low Low
Spinal Cord Injury 18 5.00 Very Low Very Low Very Low
Targeted Disruption 16 5.00 Very Low Very Low Very Low
INFLAMMATION 14 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IPFP cells at passage 2 expanded with and without FGF-2 stained strongly for CD13, CD44, CD90, and CD105 (markers for mesenchymal stem cells) and for CD29 (?
Localization (markers) of CD29 in stem cells associated with peripheral arterial disease
1) Confidence 0.29 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575620 Disease Relevance 0.48 Pain Relevance 0
Further analysis revealed that the EGFP positive cells were indeed hMSC-NT3-EGFP cells as they stained positive for antibodies directed against human CD29 and CD73, both markers present on parental hMSC-NT3-EGFP cells (Figure 7, hCD29 vs. hCD73 dot plot on EGFP-positive cells).
Localization (directed) of CD29
2) Confidence 0.13 Published 2007 Journal BMC Biotechnol Section Body Doc Link PMC2225398 Disease Relevance 0.09 Pain Relevance 0.06
EGFP-negative cells present in the cultures displayed a clearly different morphology (data not shown) and presumably were rat fibroblast cells as they were not recognized by antibodies directed against human CD29 and CD73 (Figure 7, hCD29 vs. hCD73 dot plot on EGFP-negative cells).
Localization (directed) of CD29 in fibroblast
3) Confidence 0.13 Published 2007 Journal BMC Biotechnol Section Body Doc Link PMC2225398 Disease Relevance 0.14 Pain Relevance 0.07

General Comments

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