INT222065

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RPL14) structural constituent of ribosome (RPL14) ribosome (RPL14)
RNA binding (RPL14) intracellular (RPL14) translation (RPL14)
Anatomy Link Frequency
L14 3
RPL14 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 9 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
transdermal 3 5.00 Very Low Very Low Very Low
endometriosis 3 5.00 Very Low Very Low Very Low
Dismenorea 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 273 99.12 Very High Very High Very High
Disease 30 5.00 Very Low Very Low Very Low
Toxicity 15 5.00 Very Low Very Low Very Low
Parkinson's Disease 9 5.00 Very Low Very Low Very Low
Prostate Cancer 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Myoma 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Precocious Puberty 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test the effect of glycosaminoglycans on fibril formation and peptide release, the fibril formation and monomer release profiles of samples of compounds L13 and L14 were measured in absence and presence of low molecular weight (LMW) heparin (600 ?
L14 Binding (compounds) of in L14
1) Confidence 0.02 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225439 Disease Relevance 0.44 Pain Relevance 0
After overnight incubation in the absence of LMW heparin, both L13 and L14 samples bind Thio T indicative of amyloid formation.
L14 Binding (bind) of in L14 associated with alzheimer's dementia
2) Confidence 0.02 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225439 Disease Relevance 0.47 Pain Relevance 0
Interestingly, the presence of LMW heparin results in much higher Thio T binding for both L13 and L14 peptides (Figure S4).
L14 Binding (binding) of in L14
3) Confidence 0.02 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225439 Disease Relevance 0.45 Pain Relevance 0

General Comments

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