INT222082

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.19
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Lamp2) plasma membrane (Lamp2) lysosome (Lamp2)
Anatomy Link Frequency
row 1
Lamp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 46 86.32 High High
Thalamus 9 84.80 Quite High
cerebral cortex 2 44.84 Quite Low
Inflammatory response 1 20.40 Low Low
Calcium channel 7 5.00 Very Low Very Low Very Low
Neurobehavioral 4 5.00 Very Low Very Low Very Low
TRP channel 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gliosis 2 95.16 Very High Very High Very High
Apoptosis 4 94.12 High High
Lysosomal Storage Diseases 25 50.00 Quite Low
INFLAMMATION 2 20.40 Low Low
Disease 14 5.00 Very Low Very Low Very Low
Gauchers Disease 12 5.00 Very Low Very Low Very Low
Mucopolysaccharidoses 11 5.00 Very Low Very Low Very Low
Lysosome Storage Disease 11 5.00 Very Low Very Low Very Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
WT GC distributed in a punctate manner, and colocalized with LAMP2 (Figure 2F, column 3, row 3, GC in green, LAMP2 in red, and overlap artificially colored white).
Localization (colocalized) of LAMP2 in row
1) Confidence 0.49 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225441 Disease Relevance 0 Pain Relevance 0
(B) Co-localization of the lysosomal marker Lamp-2 (anti-Lamp2 antibody) and the IDS protein (anti-hIDS antibody) as seen in the merge, as indicated.
Localization (localization) of Lamp-2
2) Confidence 0.40 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2989894 Disease Relevance 0.19 Pain Relevance 0.19
These results support our previous finding of CPMV particle localization within LAMP-2 and ß-COP-bearing Golgi and lysosome organelles both in BalbCl7 cells [24] and murine DCs [25].
Localization (localization) of LAMP-2
3) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776531 Disease Relevance 0 Pain Relevance 0

General Comments

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