INT222091

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90aa1) protein folding (Hsp90aa1) cytosol (Hsp90aa1)
ATPase activity (Hsp90aa1) intracellular (Hsp90aa1) response to stress (Hsp90aa1)
Hsp90aa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcium channel 7 25.52 Quite Low
Central nervous system 7 5.00 Very Low Very Low Very Low
TRP channel 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lysosomal Storage Diseases 24 50.00 Quite Low
Gauchers Disease 11 5.00 Very Low Very Low Very Low
Mucopolysaccharidoses 11 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Lysosome Storage Disease 6 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Cystic Fibrosis 2 5.00 Very Low Very Low Very Low
Anaemia 1 5.00 Very Low Very Low Very Low
Pompes Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mRNA expression levels of BiP, Hsp40, and Hsp90 were increased up to 1.8-fold, 1.8-fold, and 1.9-fold, respectively, after a 7-d treatment with diltiazem, whereas the mRNA expression levels of Hsp70, GRP94, calnexin, and calreticulin were not changed significantly.
Neg (not) Regulation (changed) of Transcription (expression) of Hsp90
1) Confidence 0.09 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225441 Disease Relevance 0 Pain Relevance 0

General Comments

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