INT222180

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.48
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HNF1B, TFAM) DNA binding (HNF1B, TFAM) mitochondrion (TFAM)
nucleolus (HNF1B)
HNF1B (Homo sapiens)
TFAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 65 97.12 Very High Very High Very High
Inflammation 8 69.48 Quite High
chemokine 5 48.48 Quite Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 7 98.64 Very High Very High Very High
Multiple Sclerosis 69 97.12 Very High Very High Very High
Disease 10 92.80 High High
INFLAMMATION 9 69.48 Quite High
Apoptosis 6 29.04 Quite Low
Epstein-barr Virus 8 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To reiterate, a link between TCF2 mutation and MODY5 has been established, while type 1 diabetics have an increased risk of MS development.
MODY5 Binding (link) of TCF2 associated with multiple sclerosis and diabetes mellitus
1) Confidence 0.01 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 1.48 Pain Relevance 0.40

General Comments

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