INT222182

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.10
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ESR1) enzyme binding (ESR1) DNA binding (ESR1)
protein complex (ESR1) cytoplasm (ESR1) signal transduction (ESR1)
ESR1 (Homo sapiens)
HLA-DRB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 98.08 Very High Very High Very High
Multiple sclerosis 130 97.36 Very High Very High Very High
Spinal cord 2 75.44 Quite High
Inflammation 16 73.08 Quite High
chemokine 10 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 138 97.36 Very High Very High Very High
Injury 4 78.00 Quite High
INFLAMMATION 18 73.08 Quite High
Disease 20 71.92 Quite High
Epstein-barr Virus 16 59.76 Quite High
Infection 6 55.92 Quite High
Diabetes Mellitus 14 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased risk of MS in women has been detected with interleukin-1 receptor antagonist (IL-1RA) allele 2 [8], 5G5G genotype of plasminogen activator inhibitor 1 (PAI-1) gene [9] and interaction between estrogen receptor 1 (ESR1) and HLA-DR2 [10].
ESR1 Binding (interaction) of HLA-DR2 associated with multiple sclerosis and antagonist
1) Confidence 0.00 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 1.55 Pain Relevance 0.68
Increased risk of MS in women has been detected with interleukin-1 receptor antagonist (IL-1RA) allele 2 [8], 5G5G genotype of plasminogen activator inhibitor 1 (PAI-1) gene [9] and interaction between estrogen receptor 1 (ESR1) and HLA-DR2 [10].
estrogen receptor 1 Binding (interaction) of HLA-DR2 associated with multiple sclerosis and antagonist
2) Confidence 0.00 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 1.55 Pain Relevance 0.68

General Comments

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