INT222211

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccr1) mitochondrion (TFAM) plasma membrane (Ccr1)
nucleus (TFAM) DNA binding (TFAM) cell-cell signaling (Ccr1)
Anatomy Link Frequency
macrophages 1
T cells 1
TFAM (Homo sapiens)
Ccr1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 10 100.00 Very High Very High Very High
Multiple sclerosis 130 97.84 Very High Very High Very High
Inflammation 16 72.88 Quite High
rheumatoid arthritis 2 50.56 Quite High
Central nervous system 8 37.88 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 138 97.84 Very High Very High Very High
Diabetes Mellitus 14 82.88 Quite High
Apoptosis 12 81.88 Quite High
INFLAMMATION 18 72.88 Quite High
Disease 20 70.72 Quite High
Rheumatoid Arthritis 4 50.72 Quite High
Epstein-barr Virus 16 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that TCF2 upregulates the CC chemokine receptor 1 (CCR1) a molecule expressed on macrophages and T cells; in MS plaques, numerous CCR1-positive infiltrating macrophages and microglial cells, associated with CCL3, were found [2] and CCR1 has been associated with newly infiltrating monocytes in MS lesions [32].
TCF2 Positive_regulation (upregulates) of CCR1 in T cells associated with chemokine and multiple sclerosis
1) Confidence 0.02 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 0.95 Pain Relevance 0.34
We found that TCF2 upregulates the CC chemokine receptor 1 (CCR1) a molecule expressed on macrophages and T cells; in MS plaques, numerous CCR1-positive infiltrating macrophages and microglial cells, associated with CCL3, were found [2] and CCR1 has been associated with newly infiltrating monocytes in MS lesions [32].
TCF2 Positive_regulation (upregulates) of CCR1 in macrophages associated with chemokine and multiple sclerosis
2) Confidence 0.01 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 0.95 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox