INT222214

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr1) mitochondrion (TFAM) plasma membrane (Cxcr1)
nucleus (TFAM) DNA binding (TFAM) signal transducer activity (Cxcr1)
TFAM (Homo sapiens)
Cxcr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 100.00 Very High Very High Very High
Multiple sclerosis 65 96.60 Very High Very High Very High
chemokine 5 86.28 High High
rheumatoid arthritis 1 35.52 Quite Low
Central nervous system 4 22.84 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 100.00 Very High Very High Very High
Multiple Sclerosis 69 98.88 Very High Very High Very High
Diabetes Mellitus 7 74.40 Quite High
Apoptosis 6 66.84 Quite High
Disease 10 55.68 Quite High
Rheumatoid Arthritis 2 35.68 Quite Low
Epstein-barr Virus 8 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, CXCR1, a pro-inflammatory molecule is upregulated by TCF2.
TCF2 Positive_regulation (upregulated) of CXCR1 associated with inflammation
1) Confidence 0.03 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 1.13 Pain Relevance 0.37

General Comments

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