INT222231

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Context Info
Confidence 0.55
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.25
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl12) plasma membrane (Cxcl12)
Anatomy Link Frequency
neuron 1
nerve 1
Cxcl12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Demyelination 51 98.76 Very High Very High Very High
cytokine 16 98.24 Very High Very High Very High
dorsal root ganglion 84 97.84 Very High Very High Very High
chemokine 206 94.16 High High
ischemia 1 93.04 High High
Sciatic nerve 27 90.00 High High
imagery 17 56.88 Quite High
spinal stenosis 3 27.80 Quite Low
qutenza 19 27.68 Quite Low
Peripheral nerve injury 8 25.76 Quite Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 54 98.76 Very High Very High Very High
Ganglion Cysts 85 97.84 Very High Very High Very High
Injury 83 96.24 Very High Very High Very High
Cv Unclassified Under Development 1 93.04 High High
Neuropathic Pain 49 90.96 High High
Nervous System Injury 44 85.84 High High
Myocardial Infarction 50 76.88 Quite High
Cicatrix 6 58.80 Quite High
Apoptosis 1 53.96 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 43 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neither the pattern nor the expression levels of SDF-1 mRNA transcripts changed following focal nerve demyelination at POD14 (Additional file 2B, D).
Transcription (transcripts) of SDF-1 mRNA in nerve associated with demyelination
1) Confidence 0.55 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.50 Pain Relevance 0.09
In our study, VEGF expression level in the AdV-SDF-1 group obviously increased.
Transcription (level) of AdV-SDF-1
2) Confidence 0.51 Published 2009 Journal Mol Biol Rep Section Body Doc Link PMC2831180 Disease Relevance 0.28 Pain Relevance 0.18
Lumbar DRG in the naïve (data not shown), vehicle treated and gp120/hCD4 only treated rats were largely devoid of the SDF1 mRNA transcripts with the exception of the occasional neuron (Fig. 6D, E).
Transcription (transcripts) of SDF1 in neuron associated with dorsal root ganglion
3) Confidence 0.42 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734548 Disease Relevance 1.12 Pain Relevance 0.46
The number of cells exhibiting MCP1 (immunoreactivity) or SDF1 (mRNA transcripts), the respective ligands for the CCR2 and CXCR4 receptors, were also analyzed using the both injury paradigms.
Transcription (transcripts) of SDF1 associated with injury
4) Confidence 0.37 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734548 Disease Relevance 0.36 Pain Relevance 0.18

General Comments

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