INT222239

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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.15
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ccr2) plasma membrane (Ccr2) cytoplasm (Ccr2)
signal transducer activity (Ccr2)
Anatomy Link Frequency
nerve 2
Ccr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 42 98.72 Very High Very High Very High
Demyelination 49 89.64 High High
chemokine 154 82.76 Quite High
withdrawal 26 78.20 Quite High
c fibre 6 66.56 Quite High
nociceptor 11 65.92 Quite High
Hyperalgesia 14 65.28 Quite High
Spinal cord 9 36.56 Quite Low
Dorsal horn 4 35.60 Quite Low
Sciatic nerve 21 27.04 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 36 99.48 Very High Very High Very High
Ganglion Cysts 43 98.72 Very High Very High Very High
Demyelinating Disease 51 89.64 High High
Injury 47 85.04 High High
Hyperalgesia 26 65.28 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 22 50.00 Quite Low
Neuropathic Pain 33 5.00 Very Low Very Low Very Low
Pain 31 5.00 Very Low Very Low Very Low
Nociception 21 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Small and medium diameter L4L5 neurons ipsilateral to the focal nerve lesion exhibited low levels of both CCR2 mRNA transcripts at POD7 (Fig. 2C) and CCR2 immunoreactivity (Fig. 2D).
Transcription (transcripts) of CCR2 mRNA in nerve
1) Confidence 0.61 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.66 Pain Relevance 0.52
Following perineural gp120/hCD4, sensory neurons in the lumbar DRG ipsilateral to the focal nerve injury were observed to express CCR2 mRNA transcripts (Fig. 2C) and were immunopositive for CCR2 (Fig. 2D).
Transcription (transcripts) of CCR2 mRNA in nerve associated with dorsal root ganglion and nervous system injury
2) Confidence 0.59 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734548 Disease Relevance 0.49 Pain Relevance 0.20

General Comments

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