INT222244

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Trpv1, Ccr5) endosome (Ccr5) cytosol (Trpv1)
aging (Ccr5) cell-cell signaling (Ccr5) cytoplasm (Ccr5)
Trpv1 (Rattus norvegicus)
Ccr5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Endogenous opioid 1 100.00 Very High Very High Very High
Analgesic 1 100.00 Very High Very High Very High
chemokine 102 99.98 Very High Very High Very High
Hyperalgesia 14 98.40 Very High Very High Very High
Sciatic nerve 15 91.20 High High
Lasting pain 8 82.20 Quite High
Demyelination 47 78.96 Quite High
antagonist 14 64.16 Quite High
Antinociceptive 1 62.92 Quite High
Pain 15 59.44 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 21 98.40 Very High Very High Very High
Nervous System Injury 28 95.04 Very High Very High Very High
Pain 26 82.20 Quite High
Demyelinating Disease 48 78.96 Quite High
Injury 14 44.88 Quite Low
Disease 1 44.08 Quite Low
Neuropathic Pain 17 5.00 Very Low Very Low Very Low
Nociception 14 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 11 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chemokine interactions with CCR5 may also depress the analgesic action of endogenous opioids and/or sensitize TRPV1 [10,53,54] thereby generally promoting hyperalgesia.
TRPV1 Binding (interactions) of CCR5 associated with chemokine, hyperalgesia, analgesic and endogenous opioid
1) Confidence 0.19 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.57 Pain Relevance 0.86

General Comments

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