INT222268

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.21
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (UTS2R) plasma membrane (UTS2R) signal transducer activity (UTS2R)
Anatomy Link Frequency
monocytes 1
UTS2R (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 99.00 Very High Very High Very High
Crohn's disease 8 14.48 Low Low
Inflammation 14 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 45 75.72 Quite High
Myocardial Infarction 3 70.92 Quite High
Crohn's Disease 6 26.80 Quite Low
Disease 9 14.48 Low Low
Shock 3 14.24 Low Low
Cancer 3 7.92 Low Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To analyze whether the ratio of the different UTR mRNA isoforms of NOD2 is regulated by cytokine stimulation, primary human monocytes were purified and stimulated for 12 h with TNF-?
Transcription (isoforms) of UTR in monocytes associated with cytokine
1) Confidence 0.44 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2228316 Disease Relevance 0 Pain Relevance 0.05
UTR sequence of HSPA1A mRNA was comprehensively analyzed and reported to act as a general enhancer of mRNA translation[29].
Spec (analyzed) Transcription (sequence) of UTR
2) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659421 Disease Relevance 0.21 Pain Relevance 0

General Comments

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