INT222284

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Casp1, Il18) extracellular region (Casp1, Il18) intracellular (Casp1)
protein complex (Casp1) peptidase activity (Casp1) extracellular space (Il18)
Casp1 (Rattus norvegicus)
Il18 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 14 96.96 Very High Very High Very High
Inflammation 15 96.56 Very High Very High Very High
cva 19 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Clonidine 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 17 96.56 Very High Very High Very High
Pneumonia 7 87.64 High High
Endotoxemia 5 86.40 High High
Critical Illness 27 70.64 Quite High
Sepsis 38 60.16 Quite High
Brain Injury 21 50.00 Quite Low
Renal Failure 1 50.00 Quite Low
Stress 3 34.48 Quite Low
Apoptosis 8 33.28 Quite Low
Bacterial Infection 3 27.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a series of elegant experiments, Boost and collaborators showed that a caspase-1 inhibitor administered by inhalation in endotoxemic rats decreased IL-1 and IL-18 levels in bronchoalveolar lavage fluid [18].
Negative_regulation (inhibitor) of caspase-1 Negative_regulation (decreased) of IL-18
1) Confidence 0.01 Published 2008 Journal Intensive Care Med Section Body Doc Link PMC2228383 Disease Relevance 0.79 Pain Relevance 0.46

General Comments

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