INT222300

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.89
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ERBB2, PGR) signal transduction (ERBB2, PGR) nucleus (ERBB2, PGR)
nucleoplasm (PGR) enzyme binding (PGR) DNA binding (PGR)
ERBB2 (Homo sapiens)
PGR (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 24 86.20 High High
imagery 2 49.88 Quite Low
cva 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
sSRI 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Gabapentin 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 62 99.12 Very High Very High Very High
Metastasis 17 97.56 Very High Very High Very High
Breast Cancer 19 95.64 Very High Very High Very High
Disease 19 91.92 High High
Reprotox - General 1 48 89.56 High High
Advanced Or Metastatic Breast Cancer 11 85.04 High High
Recurrence 9 80.92 Quite High
Death 24 67.16 Quite High
Arthralgia 10 57.20 Quite High
Solid Tumor 2 52.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subgroups were classified on the basis of ER, PR, and HER2 IHC findings with 71 of the 110 patients (64.5%) being HR+, 14 patients (12.7%) HER2+, and 25 patients (22.7%) TN.
HER2 Binding (findings) of PR
1) Confidence 0.34 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2972282 Disease Relevance 0.62 Pain Relevance 0.09
Subgroups were classified on the basis of ER, PR, and HER2 IHC findings with 71 of the 110 patients (64.5%) being HR+, 14 patients (12.7%) HER2+, and 25 patients (22.7%) TN.
HER2 Binding (findings) of PR
2) Confidence 0.29 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2972282 Disease Relevance 0.63 Pain Relevance 0.09
Patients who have ER-positive tumours with unfavourable characteristics, such as HER-2 positivity, PgR negativity or nodal positivity, are likely to be selected for immediate AI therapy.
HER-2 Neg (negativity) Binding (negativity) of PgR associated with cancer
3) Confidence 0.02 Published 2007 Journal International Journal of Clinical Practice Section Body Doc Link PMC2228389 Disease Relevance 0.65 Pain Relevance 0

General Comments

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