INT2224

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Context Info
Confidence 0.49
First Reported 1979
Last Reported 1979
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.07

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cytoplasm (Ranbp1)
Anatomy Link Frequency
neurons 1
Ranbp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 1 75.64 Quite High
Sciatic nerve 1 72.20 Quite High
neuralgia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 99.08 Very High Very High Very High
Anaerobic Bacterial Infections 1 80.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have found that (1) although Ran-1 is expressed on glial and neuronal tumours, it was not found on normal astrocytes, oligodendrocytes or neurons; (2) Thy-1 was present on fibroblasts and some neurons but not on the majority of leptomeningeal cells or on oligodendrocytes or astrocytes in short-term cultures (however, it was expressed on some astrocytes in longer term cultures); (3) the 'large external transformation sensitive' (LETS) protein could be detected on fibroblasts and leptomeningeal cells but not on neurons or glial cells; (4) GM1 was present on all neurons, most oligodendrocytes and approx. 50% of other cell types; sulfatide and GM3 were only detectable on oligodendrocytes, while globoside was only found on some neurons.
Gene_expression (expressed) of Ran-1 in neurons associated with cancer
1) Confidence 0.49 Published 1979 Journal Brain Res. Section Abstract Doc Link 385109 Disease Relevance 0.18 Pain Relevance 0.07

General Comments

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