INT222608

Context Info Confidence 0.10 First Reported 2008 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 0.29 Pain Relevance 0.03

cytoplasm (Acvr2a)

Acvr2a (Rattus norvegicus)

Pain Link Frequency Relevance Heat Action potential 7 69.88 antagonist 78 5.00 Nerve growth factor 56 5.00 Inflammation 54 5.00 cytokine 44 5.00 agonist 44 5.00 Calcitonin gene-related peptide 34 5.00 substance P 32 5.00 gABA 30 5.00 Dopamine 26 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 65 99.70 Sunburn 1 55.64 Repression 2 25.52 Stress 97 5.00 INFLAMMATION 56 5.00 Cancer 44 5.00 Pituitary Cancer 22 5.00 Starvation 20 5.00 Rheumatoid Arthritis 16 5.00 Natriuresis 14 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, in castrated mice in which the gene for activin receptor type II (Act-R-II) was disrupted, FSH?

Negative_regulation (disrupted) of Gene_expression (gene) of activin receptor type II

1) Confidence 0.10 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0 Pain Relevance 0

Similarly, in castrated mice in which the gene for activin receptor type II (Act-R-II) was disrupted, FSH?

Negative_regulation (disrupted) of Gene_expression (gene) of Act-R-II

2) Confidence 0.10 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0 Pain Relevance 0

In the present study, we established several lines of transgenic rats in which ChR2 expression was driven by the Thy-1.2 promoter.

Negative_regulation (driven) of Gene_expression (expression) of ChR2 associated with targeted disruption

3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2772120 Disease Relevance 0.29 Pain Relevance 0.03

General Comments

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