INT222662

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a, INCENP) chromosome segregation (INCENP) protein complex (INCENP)
cytoplasm (INCENP) extracellular space (Il1a) extracellular region (Il1a)
Anatomy Link Frequency
pituitary 2
Il1a (Rattus norvegicus)
INCENP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 62.36 Quite High
cytokine 22 55.44 Quite High
adenocard 3 25.12 Quite Low
antagonist 39 5.00 Very Low Very Low Very Low
Nerve growth factor 28 5.00 Very Low Very Low Very Low
agonist 22 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 17 5.00 Very Low Very Low Very Low
substance P 16 5.00 Very Low Very Low Very Low
gABA 15 5.00 Very Low Very Low Very Low
Dopamine 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 48 80.60 Quite High
Targeted Disruption 22 63.20 Quite High
INFLAMMATION 28 62.36 Quite High
Cancer 22 5.00 Very Low Very Low Very Low
Pituitary Cancer 11 5.00 Very Low Very Low Very Low
Starvation 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Natriuresis 7 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Hyperplasia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bilezikjian and colleagues have shown that LPS enhances expression of follistatin and activin B in the pituitary in vivo (716), that FS cells are targets for IL-1 (95) and that IL-1 augments the production of follistatin both in vivo and in vitro, thereby attenuating FSH output in response to activins (716).
IL-1 Positive_regulation (augments) of Gene_expression (production) of in vivo in pituitary
1) Confidence 0.00 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.32 Pain Relevance 0.08

General Comments

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