INT222685

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.63
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TEAD1) DNA binding (TEAD1)
TEAD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 12 97.96 Very High Very High Very High
Central nervous system 39 63.36 Quite High
cva 27 5.00 Very Low Very Low Very Low
Electroencephalography 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 97.96 Very High Very High Very High
Apoptosis 6 94.96 High High
Sepsis 107 94.88 High High
Hemorrhage 172 92.24 High High
Infection 6 74.00 Quite High
Hypersensitivity 3 73.68 Quite High
Encephalopathy 36 71.24 Quite High
Respiratory Failure 1 68.00 Quite High
Death 27 60.68 Quite High
Body Weight 3 49.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the 34 test drugs, eight were defined as visually compatible with DrotAA.


DrotAA Binding (compatible) of
1) Confidence 0.27 Published 2007 Journal Crit Care Section Body Doc Link PMC2230610 Disease Relevance 0.33 Pain Relevance 0.03
DrotAA is not recommended for use in persons under the age of 18 years and should not therefore be used in these patients.
DrotAA Binding (recommended) of
2) Confidence 0.27 Published 2007 Journal Crit Care Section Body Doc Link PMC2230610 Disease Relevance 0.47 Pain Relevance 0.06
DrotAA is not indicated for patients with single organ dysfunction and in particular should not be used in patients with single organ dysfunction and recent surgery.


DrotAA Binding (indicated) of
3) Confidence 0.27 Published 2007 Journal Crit Care Section Body Doc Link PMC2230610 Disease Relevance 0.37 Pain Relevance 0
DrotAA also binds directly to specific receptors on endothelial and inflammatory cells, thereby modulating and downregulating inflammatory and apoptotic processes [2].
DrotAA Binding (binds) of associated with inflammation and apoptosis
4) Confidence 0.00 Published 2010 Journal Crit Care Section Body Doc Link PMC2887172 Disease Relevance 1.46 Pain Relevance 0.17

General Comments

This test has worked.

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