INT222711

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.28
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Clca3) extracellular region (Clca3)
Anatomy Link Frequency
Goblet cell 1
Clca3 (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 81 97.44 Very High Very High Very High
cytokine 48 91.08 High High
chemokine 36 84.12 Quite High
Inflammation 33 67.16 Quite High
agonist 78 44.92 Quite Low
fibrosis 6 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 123 99.92 Very High Very High Very High
Hyperplasia 15 98.96 Very High Very High Very High
Obstructive Airway Disease 3 93.36 High High
INFLAMMATION 36 67.16 Quite High
Necrosis 3 64.92 Quite High
Cancer 3 64.56 Quite High
Airway Remodeling 12 11.36 Low Low
Disease 24 5.00 Very Low Very Low Very Low
Fibrosis 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Little expression of either Gob-5 or Muc5-ac mRNA was observed in control mice, but levels more than 500 (Gob-5; P < 0.05) or 20 (Muc5-ac; P < 0.05) times greater were seen in CRA-challenged mice (Fig. 4B).
Transcription (expression) of Gob-5
1) Confidence 0.42 Published 2007 Journal Respir Res Section Body Doc Link PMC2231357 Disease Relevance 0.34 Pain Relevance 0.31
2 effectively reduces mucin production and Gob-5 and Muc5-ac mRNA expression
Transcription (expression) of Gob-5
2) Confidence 0.42 Published 2007 Journal Respir Res Section Body Doc Link PMC2231357 Disease Relevance 0.60 Pain Relevance 0.58
Goblet cell hyperplasia and mucin production are associated with increased transcription of the Gob-5 and Muc5-ac genes [24,36].
Transcription (transcription) of Gob-5 in Goblet cell associated with hyperplasia
3) Confidence 0.42 Published 2007 Journal Respir Res Section Body Doc Link PMC2231357 Disease Relevance 0.35 Pain Relevance 0.32

General Comments

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