INT222784

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL13, MR1) signal transduction (IL13) extracellular space (IL13)
endoplasmic reticulum (MR1) plasma membrane (MR1) cell-cell signaling (IL13)
Anatomy Link Frequency
monocytes 2
IL13 (Homo sapiens)
MR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 15 99.86 Very High Very High Very High
Inflammation 1 67.28 Quite High
lidocaine 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 66 98.44 Very High Very High Very High
Dengue 15 84.80 Quite High
INFLAMMATION 1 67.28 Quite High
Disease Progression 1 35.72 Quite Low
Flavivirus Infection 7 30.68 Quite Low
Sprains And Strains 7 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low
Asthma 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also show that pre-treatment of primary human monocytes with Th2 cytokines (IL-4/IL-13), which upregulate MR expression, increases their susceptibility to DV infection in vitro.
IL-13 Positive_regulation (upregulate) of Gene_expression (expression) of MR in monocytes associated with infection and cytokine
1) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233670 Disease Relevance 0.53 Pain Relevance 0.08

General Comments

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