INT222805

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.32
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (MRC1) plasma membrane (MRC1)
Anatomy Link Frequency
monocytes 1
MRC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 95.88 Very High Very High Very High
cytokine 15 76.72 Quite High
abdominal pain 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rubella Virus Infection 144 100.00 Very High Very High Very High
Togavirus Infection 53 100.00 Very High Very High Very High
Autism 17 97.36 Very High Very High Very High
INFLAMMATION 6 95.88 Very High Very High Very High
Immunization 66 89.24 High High
Mumps 106 76.64 Quite High
Disease 39 67.48 Quite High
Sprains And Strains 54 66.72 Quite High
Infection 83 66.16 Quite High
Disease Progression 1 64.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found the age at the time of exposure to MMR relative to onset of GI problems in cases and controls and the temporal order of MMR administration, GI episodes, and AUT onset in cases to be inconsistent with a causal role for MMR vaccine as a trigger or exacerbator of either GI disturbances or autism.
Positive_regulation (role) of MMR associated with autism and togavirus infection
1) Confidence 0.33 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2526159 Disease Relevance 1.17 Pain Relevance 0.04
In 1986 the Dutch Minister of Health justified his decision to introduce MMR to the national vaccination programme by reference to studies conducted elsewhere, and despite the lack of cost-effectiveness studies carried out in the Netherlands itself.
Positive_regulation (introduce) of MMR associated with rubella virus infection
2) Confidence 0.12 Published 2010 Journal Social Science & Medicine (1982) Section Body Doc Link PMC2941041 Disease Relevance 0.30 Pain Relevance 0
In September 1985 the government Minister responsible requested the Health Insurance Council (Ziekenfondsraad) to consider the financial implications of introducing MMR.
Positive_regulation (introducing) of MMR associated with rubella virus infection
3) Confidence 0.11 Published 2010 Journal Social Science & Medicine (1982) Section Body Doc Link PMC2941041 Disease Relevance 1.40 Pain Relevance 0
Protein expression studies and transcriptional profiling have shown that IL-4 induces upregulation of several receptors, including the mannose receptor (MR) on monocytes and MØ [18,19].
Positive_regulation (upregulation) of mannose receptor in monocytes
4) Confidence 0.03 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233670 Disease Relevance 0.45 Pain Relevance 0.12

General Comments

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