INT222836

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.98
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Chuk) nucleus (Chuk) kinase activity (Chuk)
cytoplasm (Chuk)
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 18 88.48 High High
Inflammation 52 67.68 Quite High
cytokine 22 54.48 Quite High
agonist 43 50.00 Quite Low
dexamethasone 3 13.12 Low Low
chemokine 13 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 5 89.76 High High
INFLAMMATION 75 88.48 High High
Infection 89 85.84 High High
Adhesions 7 85.24 High High
Repression 4 68.72 Quite High
Apoptosis 35 67.52 Quite High
Metastasis 14 61.12 Quite High
Cancer 155 53.92 Quite High
Hematologic Neoplasms 39 50.00 Quite Low
Pox Virus Infection 36 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
(Figure 3) and inhibited phosphorylation of IKK?
Negative_regulation (inhibited) of Phosphorylation (phosphorylation) of IKK
1) Confidence 0.16 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0 Pain Relevance 0
B activation by preventing phosphorylation of IKK?
Negative_regulation (preventing) of Phosphorylation (phosphorylation) of IKK
2) Confidence 0.11 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0.26 Pain Relevance 0.11
B activation and also suggest a model in which B14 inhibits activation of the IKK complex by preventing phosphorylation of IKK?
Negative_regulation (preventing) of Phosphorylation (phosphorylation) of IKK
3) Confidence 0.11 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0 Pain Relevance 0
In summary, VACV virulence factor B14 inhibits the IKK signalosome by preventing phosphorylation of IKK?
Negative_regulation (preventing) of Phosphorylation (phosphorylation) of IKK
4) Confidence 0.11 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0.24 Pain Relevance 0.08
B by decreasing phosphorylation of IKK and I?
Negative_regulation (decreasing) of Phosphorylation (phosphorylation) of IKK
5) Confidence 0.04 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.48 Pain Relevance 0

General Comments

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