INT222874

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.57
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Chuk) transport (NDUFA6) mitochondrion (NDUFA6)
small molecule metabolic process (NDUFA6) nucleus (Chuk) kinase activity (Chuk)
NDUFA6 (Homo sapiens)
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 16 85.20 High High
Inflammation 28 74.44 Quite High
cytokine 20 71.20 Quite High
chemokine 12 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 88 99.76 Very High Very High Very High
Sprains And Strains 20 90.88 High High
INFLAMMATION 48 84.84 Quite High
Pox Virus Infection 36 79.56 Quite High
Cancer 8 25.00 Low Low
Death 4 25.00 Low Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of B14 on IKK activity in the absence of other VACV-encoded NF-?
B14 Regulation (effect) of IKK
1) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0.52 Pain Relevance 0
To study the effect of B14 on IKK activity further, the IKK complex was activated by overexpression of either IKK?
B14 Regulation (effect) of IKK
2) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0.12 Pain Relevance 0
compared to cells infected with control viruses expressing B14, suggesting B14 affects IKK activity.
B14 Regulation (affects) of IKK
3) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Abstract Doc Link PMC2233672 Disease Relevance 0.63 Pain Relevance 0.15
To investigate whether the endogenous levels of B14 could affect IKK activity during virus infection, the phosphorylation status of I?
B14 Regulation (affect) of IKK associated with infection
4) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0.30 Pain Relevance 0

General Comments

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