INT222884

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.68
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 89 100.00 Very High Very High Very High
cytokine 62 100.00 Very High Very High Very High
Inflammatory mediators 7 87.28 High High
Inflammatory response 11 54.16 Quite High
Inflammatory marker 10 32.64 Quite Low
nud 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 122 100.00 Very High Very High Very High
Periodontitis 8 99.72 Very High Very High Very High
Colitis 62 99.70 Very High Very High Very High
Periodontal Disease 52 96.24 Very High Very High Very High
Mouth Disease 3 95.00 High High
Bacterial Respiratory Disease 3 88.40 High High
Disease 105 82.88 Quite High
Infection 49 78.80 Quite High
Body Weight 30 78.48 Quite High
Dental Plaque 1 74.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
colitis significantly suppressed mRNA levels of IL-1?
Negative_regulation (suppressed) of Transcription (levels) of IL-1 associated with colitis
1) Confidence 0.05 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC2233768 Disease Relevance 0.40 Pain Relevance 0.21
Treatment of colitic animals with the essential oils decreased the mRNA levels of pro-inflammatory cytokines IL-1?
Negative_regulation (decreased) of Transcription (levels) of IL-1 associated with inflammation and cytokine
2) Confidence 0.05 Published 2007 Journal Mediators of Inflammation Section Abstract Doc Link PMC2233768 Disease Relevance 0.44 Pain Relevance 0.14
In patients with advanced periodontitis, substantial reduction of IL-1 levels occurred after treatment (Masada et al 1990).
Negative_regulation (reduction) of Transcription (levels) of IL-1 associated with periodontitis
3) Confidence 0.04 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2626915 Disease Relevance 1.84 Pain Relevance 0.14

General Comments

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