INT222974

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.60
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (NFKBIB, NFKB2) cytosol (NFKBIB, NFKB2) signal transduction (NFKBIB, NFKB2)
nucleus (NFKBIB, NFKB2) nucleoplasm (NFKB2) extracellular matrix organization (NFKB2)
Anatomy Link Frequency
liver 2
NFKBIB (Homo sapiens)
NFKB2 (Homo sapiens)
ICAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 8 84.40 Quite High
cytokine 21 77.92 Quite High
Inflammation 19 77.52 Quite High
Chronic pancreatitis 33 59.52 Quite High
chemokine 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 7 99.40 Very High Very High Very High
Fibrosis 21 98.52 Very High Very High Very High
Injury 2 97.44 Very High Very High Very High
Stress 1 96.36 Very High Very High Very High
Primary Sclerosing Cholangitis 77 84.84 Quite High
INFLAMMATION 20 77.52 Quite High
Pancreatitis 33 59.52 Quite High
Necrosis 1 25.68 Quite Low
Apoptosis 2 25.32 Quite Low
Sepsis 15 24.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, inhibition of NFkB by IkB has been shown to decrease IL-6 and ICAM-1 levels in rat hepatic stellate cells during experimental liver injury [24].
IkB Negative_regulation (inhibition) of NFkB in liver Negative_regulation (decrease) of ICAM-1 associated with cirrhosis and injury
1) Confidence 0.00 Published 2007 Journal J Transl Med Section Body Doc Link PMC2234395 Disease Relevance 1.60 Pain Relevance 0.33

General Comments

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